It is a vermicide, larvicide and ovicide in gastrointestinal and pulmonary parasitosis.
Due its ovicide effect it prevents contamination from pastures and stables, which is a key factor in getting rid of the infection.
Fenbendazole is a benzimidazole methylcarbonate of great anthelminthic capacity. Its action mechanism is through union to the tubulin protein and in this way it inhibits the polymerization of same to form microtubules. These form part of the cytoskeleton and, besides, participatein the transport of nutrients and the elimination of metabolites.
Trichlorfon is an organophosphate compound which confers a larvicide and ovicide function to the antiparasite formula by generating the irreversible inhibition of the enzyme acetylcholinesterase which leads to the blockade of the hydrolysis of acetylcholine in sites of cholinergic transmission. Due to the hepatic metabolism which this antiparasite has, a liver protector, Methionine is included. This works by providing methyl and sulphur to form choline and by eliminating certain toxic compounds in the organism.

Indications for Use

This antiparasite acts on nematodes, cestodes and trematodes in general, but it is excellent for combating parasitosis caused by Ascaris, Parascaris, Strongylus vulgaris and edentatus, Strongyloides westeri, Habronema and Triodontotus.

Via of Administration and Dosage

- ½ syringe equivalent to 19 g of paste for a 500 kbv animal, equivalent to a dosage of each active ingredient:
- Fenbendazole: 5.7 mg/kbv
- Triclorfon: 19 mg/kbv
- DL-Methionine: 4.7 mg/kbv

Contraindications

We recommend that it should not be used with female horses in the last three months of pregnancy nor in colts less than 6 months old.
Do not administer with other organophosphates or inhibitors of acetylcholinesterase.
Do not administer together with phenothazine tranquillizers nor with anesthetics 10 days before and after application.

Warning

Keep the product in a clean, dry place between 15º and 25ºC out of children's reach.
Veterinary use.

Formula

• Febendazole 15 g
• Triclorfon 50g
• DL – Metionine12,5 g
• Excipients c.s.p.100 ml

Presentation

1 syringe containing 38 g of paste.

Ivermectin is a macrocyclic lactone derivative with broad and potent antiparasitic activity against nematodes. It acts by inhibiting nerve impulses. Its unique mode of action involves glutamate-gated chloride ion channels. Ivermectin binds selectively and with high affinity to glutamate-gated chloride ion channels found in invertebrate muscle and nerve cells. This leads to an increase in cell membrane permeability to chloride ions, with hyperpolarization of the nerve or muscle cell, resulting in paralysis and death of the affected parasites. Complexes of this class can also interact with other ligand-gated chloride channels, such as those opened by the neurotransmitter gamma-aminobutyl acid (GABA). The safety margin for complexes of this class is due to the fact that mammals do not have chloride channels opened by glutamate.
Praziquantel is a pyrazinoisoquinoline that exerts its anthelmintic activity against many species of cestodes and trematodes. It acts primarily by impairing the motility and function of cestode larvae. Its mode of action includes altering neuromuscular coordination, also influencing the permeability of the worm's integument, leading to excessive loss of calcium and glucose. This induces spasmodic paralysis of the parasite's musculature.

Indications for use

This product is suitable for the control and treatment of gastro-intestinal, pulmonary and skin infestations which affect horses.
Target Species
Adult horses

Via of Administration and dosage

Administer 1 g every 75 kbw. (Equivalent to 0.200 μg of ivermectin/kbw and 2.5 mg/kbw of praziquantel).
Administration is oral.
The contents of the 24 g syringe are sufficient to treat three animals weighing 600 kg each.
It is recommended to deworm animals every 90 days.
The frequency of administration will be at the discretion of the attending veterinary professional.

CONTRAINDICATIONS

Do not administer to animals in poor general condition or under intense stress.
Do not administer to horses with liver and/or kidney damage.

WARNINGS

Do not administer to animals with proven hypersensitivity to any of the formulation's components.
Store the product between 15 and 25°C.
Keep out of reach of children and pets.
For veterinary use.

Formula

• Ivermectin 1.50 g
• Praziquantel 18.75 g
• Propylene glycol csp 100 g

Presentation

The product comes in a syringe containing 38 g of paste or 24 g of paste.